Heart Transplantation

• Heart transplantation from non heart beating donors (Hendrik T. Tevaearai Stahel)
• Literature (By Ivan Knezevic)
• The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: A 10-year update (Various contributors)
• Antibody-Mediated Rejection in Cardiac Transplantation: Emerging Knowledge in Diagnosis and Management (Various contributors)
• Report from a consensus conference on antibody-mediated rejection in heart transplantation (Various contributors)
• Heart Transplantaion E-Book (Cristiano Amarelli)

Indications for heart transplantation: screening and listing of transplant candidates (Maria Frigerio)

• The framework: Need, risk factors, availability, concurrent and alternative options
• Evaluation of the chronic patient: Summary of updated ISHLT guidelines
• Evaluation of the chronic patient: Cardiological workup
• Evaluation of the chronic patient: Prognostication in advanced heart failure
• Evaluation of the chronic patient: Non-cardiac workup
• Evaluation of the chronic patient: Survival after transplantation and risk factors
• Evaluation of the acute/de novo patient
• Follow-up and management on the waiting list

Management of bi-ventricular assist device (ECMO-TAH-BIVAD) in the waiting list patient. (Cristiano Amarelli)

• Clinical context: pathophysiology over right ventricular dysfunction
• Clinical context: End organ dysfunction
• Available devices: Bridge to decision policy
• Available devices: Total artificial heart vs BiVAD
• Role of IABP
• Case & conclusions

Cardiac procurement (Ivan Knezevic)

• Donor heart inspection
• Donor heart harvesting

Cardiac preservation (Ivan Knezevic)

• Overview of preservation
• Cold static preservation
• Machine perfusion preservation

Allocation strategies: which organ for which recipient (Andreas Zuckermann)

• Donor selection: Waiting times and donor situation in Europe
• Donor selection: Donor selection
• Donor selection: Donor age and echo
• Donor selection: Hypotrophic and CAD
• Donor selection: Donor risk scores

Cardiac implantation (Andreas Zuckermann)

• Preparation of recipient
• Native heart excision
• Donor heart preparation
• Implantation technique
• Finishing & complications

Indications for transplant: screening and listing of transplant candidate - Case Development (Josebe Goirigolzarri)

• Indications for transplant: Screening and listing of transplant candidate
• Right heart catheterization and comorbidities
• Pulmonary hypertension management
• INTERMACS III strategies and how the case ends

Selecting patients for LVAD implantation: troubles and hopes of an heart failure cardiologist: Case 1 (Marco Masetti)

• Introduction to LVAD
• Case 1: Urgent or not? Complicated LVAD on the waiting list
• Case 1: Complications
• Case 1: Solution

Heart Transplantation - Surgical Procedures (Ivan Knezevic)

• Donor heart harvesting: Tricks & tips
• The heart recipient operation: Tricks & tips
• Donor heart implantation - bicaval technique: Tricks & tips

Immunosuppression in heart transplantation (Luciano Potena)

• General principles of immunosuppression in heart transplantation
• Induction therapy
• Maintenance therapy
• Long term therapeutic objectives
• Key principles and learnings

Theatre Lecture: Journey of a Biopsy: Part I (Luciano Potena)

• Journey of a Biopsy: Part I

Lab Lecture: Journey of a Biopsy: Part II (Ornella Leone)

• Technical preparation of the biopsy
• Pathology of cardiac rejection
• Case 1: Negative for rejection
• Case 2: Moderate rejection
• Case 3: Mild rejection
• Case 4: Antibody mediated rejection
• Case 5: Mixed rejection

Heart transplants in patients with congenital heart disease and previous palliative procedures (Daniel Zimpfer)

• Morphology and Anatomy
• Donor selection and organ procurement
• Transplant procedure
• Reconstruction of central pulmonary arteries and venous return

Selecting patients for LVAD implantation: troubles and hopes of an heart failure cardiologist: Case 2 (Marco Masetti)

• Case 2: Severe pulmonary hypertension in transplant candidate - end of the story?
• Case 2: Solution

Selecting patients for LVAD implantation: troubles and hopes of an heart failure cardiologist: Case 3 (Marco Masetti)

• Case 3: Cardiogenic shock of 20 year old female soccer player with recent cancer
• Case 3: Solution & RV failure

Transplantation in congenital heart disease (CHD) in pediatric and adult patients - Indication, Timing, Pre-operative diagnostics (Martin Schweiger)

• Main reasons for HT in CHD
• Special considerations for HT in CHD
• ACHD
• Failing Fontan

Early management: preventing, recognising and managing complications (Nick Banner)

• Background of heart transplantation with complications
• Casestudy introduction
• Circulatory failure after heart transplantation
• Allograft dysfunction - definition and existing assessment models
• Allograft dysfunction - a different view

Long term management and complications: Case Presentation (Josebe Goirigolzarri)

• Long term management and complications: Infections and IS
• CMV initial management
• Drug resistant CMV
• Immunosuppresion: Introduction
• Immunosuppresion: General principles

Long term management and complications: Case Presentation (Josebe Goirigolzarri)

• Long term management and complications: CAD and rejection
• AMR diagnosis in our patient
• Brief lecture of AMR: Risks, diagnosis and treatment